Charleston International Airport (CHS)
5500 International Blvd, Charleston, SC 29418
Toronto-Pearson (Canada)
Charlotte, Dallas/Ft. Worth, Miami, Philadelphia
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Seasonal: Chicago-O'Hare, Washington-National
Akron/Canton, Albany, Atlantic City (Begins 5/6/26), Cincinnati, Columbus-Glenn, Fort Myers, Hartford, Long Island/Islip, Louisville, Manchester (NH), New Haven, New Orleans, Newburgh, Norfolk, Orlando, Pittsburgh, Portland (ME), Providence, Richmond, Rochester (NY), Syracuse, Tampa, White Plains
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Seasonal: Burlington (VT), Cancun (Mexico), Los Angeles, West Palm Beach
Dallas/Ft. Worth
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Seasonal: Philadelphia
Fort Lauderdale, Newark
Chicago-O'Hare, Houston-Intercontinental, Newark, Washington-Dulles
Seattle/Tacoma
Charlotte, Chicago-O'Hare, Miami, New York-LaGuardia, Philadelphia, Washington-National
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Seasonal: Dallas/Ft. Worth
Atlanta, Boston, Minneapolis/St. Paul, New York-LaGuardia
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Seasonal: Detroit
Boston, Fort Lauderdale, New York-JFK
Sun Country Airlines
Seasonal: Minneapolis/St. Paul
Cincinnati
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Seasonal: Columbus-Rickenbacker, Indianapolis, Louisville
Seasonal: New Haven
Boston, Detroit, New York-JFK, New York-LaGuardia
Baltimore, Chicago-Midway, Dallas-Love, Denver, Houston-Hobby, Nashville
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Seasonal: Austin, Kansas City, St. Louis
Chicago-O'Hare, Denver, Newark, Washington-Dulles
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Seasonal: Houston-Intercontinental
Columbia Metropolitan Airport (CAE)
3250 Airport Blvd, West Columbia, SC 29170
Fort Lauderdale, Orlando/Sanford
Atlanta
American Airlines
Seasonal: Dallas/Ft. Worth
Atlanta, New York-LaGuardia
Charlotte, Chicago-O'Hare (Begins 5/21/26), Dallas/Ft. Worth, New York-LaGuardia, Philadelphia, Washington-National
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Seasonal: Miami
Chicago-O'Hare, Newark Washington-Dulles
Florence Regional Airport (FLO)
2100 Terminal Dr, Florence, SC 29506
Charlotte
Greenville-Spartanburg International Airport (GSP)
2000 GSP Dr, Greer, SC 29651
Fort Lauderdale, Orlando/Sanford, St. Petersburg/Clearwater, Sarasota
Seasonal: New Haven
Detroit, New York-LaGuardia
Chicago-O'Hare, Denver, Houston-Intercontinental, Newark, Washington-Dulles
Charlotte, Dallas/Ft. Worth
Columbus-Glenn (Begins 5/8/26), Providence, Tampa
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Seasonal: Fort Myers, Hartford, Los Angeles, Orlando, Pittsburgh
Baltimore, Houston-Hobby, Nashville
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Seasonal: Denver
Charlotte, Chicago-O'Hare, Dallas/Ft. Worth, Miami, New York-LaGuardia, Philadelphia, Washington-National
Atlanta, Detroit
Houston-Intercontinental
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Seasonal: Chicago-O'Hare
Hilton Head Airport (HXD)
120 Beach City Rd, Hilton Head, SC 29926
Charlotte
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Seasonal: Boston, Chicago-O'Hare, Philadelphia, Washington-National
Seasonal: Atlanta, New York-LaGuardia
Seasonal: Chicago-O'Hare, Newark
Myrtle Beach International Airport (MYR)
1100 Jetport Dr, Myrtle Beach 29577
Grand Rapids
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Seasonal: Akron/Canton, Albany, Cincinnati, Clarksburg, Columbus-Rickenbacker, Dayton (Begins 5/22/26), Elmira (Begins 5/22/26), Fort Wayne, Hagerstown (MD), Harrisburg, Huntington, Indianapolis, Lexington, Louisville, Niagara Falls, Pittsburgh, Plattsburgh, St. Louis/Belleville, Syracuse
New Haven
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Seasonal: Wilmington (DE)
New York-LaGuardia
​Seasonal: Atlantic City, Chicago-O'Hare, Cleveland, Detroit, Hartford, Latrobe, Louisville, Nashville, Rochester
Newark​
Charlotte, Chicago-O'Hare, Dallas/Ft. Worth
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Seasonal: Boston
Fort Lauderdale, Long Island/Islip (Begins 5/6/26), Manchester (NH), New Orleans, Orlando, Providence, Rochester (NY), Tampa, White Plains
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Seasonal: Akron/Canton, Charleston (WV), Hartford, Wilkes-Barre/Scranton
Seasonal: Cleveland, Long Island/Islip, Philadelphia, Trenton
Seasonal: Minneapolis/St. Paul
Charlotte, Philadelphia, Washington-National​
Atlanta
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Seasonal: Boston, Minneapolis/St. Paul
Baltimore, Chicago-Midway, Nashville
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Seasonal: Columbus-Glenn, Dallas-Love, Denver, Kansas City, Pittsburgh, St. Louis
Seasonal: Chicago-O'Hare, Denver, Washington-Dulles